It's understandable.
Gakpo is on the left. Ekitike likes to drift left. Wirtz likes the left half-space.
Trent and Elliott (when played) tended to be part of triangulation of the ball on the right-hand side of the pitch. Szoboszlai now won't be playing in that right-sided 8 position on a week-in, week-out basis and Frimpong will play a totally different style to Trent when he features.
We're also playing an increasingly patient game, so the long diagonal from Van Dijk to Salah will probably occur less often.
All adds up - it's certainly very interesting (probably moreso for a neutral who doesn't "worry" about it as it ain't their team) but undeniably will raise some questions about getting the best out of a Ł400k-per-week player.
Do feel that there is a thought process behind becoming less reliant on Mo and that the tweaks are partly because of that.